Allergic reactions can occur with celecoxib. Individuals who have developed allergic reactions (rash, itching, difficulty breathing) from sulfonamides (for example, sulfamethoxazole and trimethoprim [Bactrim]), aspirin or other NSAIDs may experience an allergic reaction to celecoxib and should not take celecoxib.
NSAIDs (except for low-dose aspirin) may increase the risk of heart attacks, stroke, and related conditions, which can be fatal. This risk may increase with duration of use and in patients who have underlying risk factors for heart and blood vessel conditions. NSAIDs should not be used for the treatment of pain resulting from coronary artery bypass graft (CABG) surgery.
NSAIDs cause an increased risk of serious, even fatal, stomach and intestinal adverse reactions such as bleeding, ulcers, and perforation of the stomach or intestines. These events can occur at any time during treatment and without warning symptoms. Elderly patients are at greater risk for these types of reactions.
GENERIC AVAILABLE: Yes
PREPARATIONS: Capsules: 50, 100, 200, and 400 mg
STORAGE: Capsules should be stored between 15 C and 30 C (59 F and 86 F).
DOSING: The lowest effective dose should be used for each patient.
- For the management of osteoarthritis, the dose usually is 100 mg twice daily or 200 mg as a single dose.
- For rheumatoid arthritis, the dose usually is 200 mg twice daily.
- For acute pain or menstrual cramps, the dose is 400 mg as a single dose on the first day followed by an additional 200 mg if needed, then 200 mg twice daily as needed.
- For FAP, the recommended dose is 400 mg twice daily.
Quick GuideOsteoarthritis (OA): Treatment, Symptoms, Diagnosis
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