cefuroxime, Ceftin, Zinacef

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GENERIC NAME: cefuroxime

BRAND NAME: Ceftin, Zinacef

DRUG CLASS AND MECHANISM: Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to penicillin. Cephalosporins stop or slow the growth of bacterial cells by preventing bacteria from forming the cell wall that surrounds each cell. The cell wall protects bacteria from the external environment and keeps the contents of the cell together. Without a cell wall, bacteria are not able to survive. Cefuroxime is effective against a wide variety of bacteria, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, E. coli, N. gonorrhea, and many others. The FDA approved cefuroxime in December 1987.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Tablets: 125, 250 and 500 mg.
  • Powder for Oral Suspension: 125 or 250 mg per 5 ml (teaspoon).
  • Injection: 750 mg, 1.5 g and 7.5 g.

STORAGE:

  • Tablets should be stored at room temperature between 15-30 C (59-86 F).
  • The oral suspension should be stored between 2-30 C (36-86F) prior to mixing and refrigerated between 2-8 C (3646 F) after mixing. The suspension should be discarded after 10 days.

PRESCRIBED FOR: Cefuroxime is effective against susceptible bacteria causing infections of the middle ear (otitis media), tonsillitis, throat infections, laryngitis, bronchitis, and pneumonia. It also is used for treating urinary tract infections, skin infections, and gonorrhea. Additionally, it is useful in treating acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD).




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