cefprozil, Cefzil (cont.)

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PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 250 and 500 mg; Powder for suspension: 125 and 250 mg/5 ml.

STORAGE: Tablets should be kept at room temperature, 15 C to 30 C (59 F to 86 F). The unmixed powder should be kept at room temperature, 15 to 25 C (59 to 77 F), refrigerated after mixing, and discarded after 14 days.

PRESCRIBED FOR: Cefprozil is effective against susceptible bacteria causing infections of the middle ear, tonsils (tonsillitis), throat (pharyngitis), larynx (laryngitis), bronchi (bronchitis), skin and soft tissues as well as pneumonia..

DOSING: Cefprozil is taken once or twice daily, depending on the nature and severity of the infection. The recommended adult dose is 250-500 mg twice daily for 10 days. Pharyngitis and tonsillitis are treated with 500 mg once daily.

The maximum dose for ear infections and sinusitis in children 6 months to 12 year old is 30 mg /kg/day in 2 divided doses given every 12 hours (not to exceed 1000 mg/day).

ppharyngitisand tonsillitis, in children (2 -12 years old) are treated with 15 /kg/day in two divided doses every 12 hours while skin infections are treated with 20 mg/kg/day (not to exceed 1000 mg/day).

DRUG INTERACTIONS: Probenecid (Benemid) may increase the blood concentration of cefprozil by decreasing excretion of cefprozil by the kidney. This interaction is sometimes used to enhance the effect of cephalosporins.

Combining cefprozil with aminoglycosides (for example, tobramycin) produces additive bacterial killing effects but also may increase the risk of harmful effects to the kidney.

Exenatide (Byetta) may delay or reduce the absorption of cephalosporins. Cephalosporins should be administered one hour before exenatide.

CCefprozil may cause false test results with some tests for sugar in the urine.

PREGNANCY: There are no adequate studies of cefprozil in pregnant women.. However, studies in animals suggest no important effects on the fetus.

NURSING MOTHERS: Small amounts of cefprozil are secreted in breast milk, but the effect on the infant is unknown.

Medically Reviewed by a Doctor on 10/10/2014


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