cefadroxil, Duricef (Discontinued) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Cefadroxil can alter the normal bacteria in the colon and encourage overgrowth of some bacteria, specifically, Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting cefadroxil (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.



PREPARATIONS: Tablets: 1 g. Capsules: 500 mg. Powder for suspension: 125, 250, and 500 mg/teaspoon (5 ml).

STORAGE: Cefadroxil should be stored at room temperature, 15 C - 30 C (59 F - 86 F). Once mixed, the suspension should be refrigerated and discarded after 14 days.

DOSING: The recommended adult dose for treating pharyngitis, skin and skin structure infections, and tonsillitis is 1 gram daily as a single dose or in two divided doses.

The dose for urinary tract infections is 2 grams once daily or in two divided doses.

The dose for preventing endocarditis is 2 grams given one hour before a procedure.

The recommended dose for children is 30 mg/kg/day as a single dose or two divided doses.

DRUG INTERACTIONS: Cefadroxil may reduce the immune response to BCG (tuberculosis vaccine) and typhoid live vaccines and result in less effective vaccination.

PREGNANCY: There are no adequate studies of cefadroxil in pregnant women.

NURSING MOTHERS: Cefadroxil is secreted in breast milk.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 9/28/2015

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