carvedilol (Coreg, Coreg CR) (cont.)

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PRESCRIBED FOR: Carvedilol is used alone or with a diuretic ("water-pill") to control high blood pressure (hypertension). Carvedilol also may be used in combination with other drugs to manage mild or moderate congestive heart failure. When combined with other treatments for heart disease among patients with recent heart attacks, carvedilol can reduce the risk of a second heart attack by 40% and increase survival among patients with congestive heart failure. It is also used for treating angina (chest pain from heart disease).

DOSING: Carvedilol tablets are usually is given twice daily. For high blood pressure, the dose may range from 6.25 mg twice daily to a maximum of 25 mg twice daily.

For congestive heart failure, the dose may range from 3.25 mg twice daily to a maximum of 25 mg twice daily in persons weighing less than 85 kg (187 pounds) or 50 mg twice daily in persons weighing more than 85 kg (187 pounds).

For treating angina the dose is 25 to 50 mg twice daily.

Carvedilol should be taken with food since this increases the amount of absorbed drug that reaches the heart and arteries. Stopping and changing doses of carvedilol should be done under the direction of a physician since sudden changes in dose can result in serious cardiac complications such as arrhythmias.

The dose range for treating heart failure or high blood pressure with extended release capsules is 10 to 80 mg once daily.

DRUG INTERACTIONS: Carvedilol can mask early warning symptoms of low blood sugar (hypoglycemia) such as tremors and increased heart rate. (These symptoms are caused by activation of the adrenergic nervous system which is blocked by the carvedilol.) Therefore, patients with diabetes taking medications that lower blood sugar such as insulin or oral anti-diabetic medications may need to increase the frequency with which they monitor their blood sugar.

Medically Reviewed by a Doctor on 8/7/2014


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