carvedilol (Coreg, Coreg CR)

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GENERIC NAME: carvedilol

BRAND NAME: Coreg, Coreg CR

DRUG CLASS AND MECHANISM: Carvedilol is used for treating high blood pressure and congestive heart failure. It is related to labetalol (Normodyne, Trandate). Carvedilol blocks receptors of the adrenergic nervous system, the system of nerves in which adrenalin (epinephrine) is active. Nerves from the adrenergic system enter the heart and release an adrenergic chemical (norepinephrine) that attaches to receptors on the heart's muscle and stimulates the muscle to beat more rapidly and forcefully. By blocking the receptors, carvedilol reduces the heart's rate and force of contraction and thereby reduces the work of the heart. Carvedilol also blocks adrenergic receptors on arteries and causes the arteries to relax and the blood pressure to fall. The drop in blood pressure further reduces the work of the heart since it is easier to pump blood against a lower pressure. The FDA first approved carvedilol in 1995.

GENERIC AVAILABLE: yes

PRESCRIPTION: yes

PREPARATION:

  • Tablets: 3.125, 6.25, 12.5, and 25 mg.
  • Capsules (Extended Release): 10, 20, 40, 80 mg

STORAGE: Tablets should be stored at room temperature, 15 C and 30 C (59 F and 86 F).

Medically Reviewed by a Doctor on 8/7/2014



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