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August 29, 2008
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GENERIC NAME: CARMUSTINE - INJECTION (kar-MUST-een)

BRAND NAME(S): BiCNU

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

WARNING: Carmustine has caused severe, even fatal, lung problems (pulmonary toxicity) and severe blood disorders (e.g., bone marrow suppression). Pulmonary toxicity may not be seen until years after this medication has been used. Notify your doctor immediately if you develop easy bruising or bleeding, breathing problems, an infection with symptoms such as persistent fever, sore throat, chills or unusual fatigue. The chances of developing these problems increase as more of this drug is used. A history of lung problems also increases the chance of pulmonary toxicity. Your doctor will monitor your blood cells for at least 6 weeks after a dose is given. Future doses may be adjusted accordingly. Doses must not be given more frequently than every 6 weeks.

USES: Carmustine is used to treat various cancers, Hodgkin's disease or tumors.

HOW TO USE: This medication is administered by infusion into a vein over a 1-2 hour period. The dose and frequency of use of this medication will be determined in part by your condition and your response to previous therapy. Follow your doctor's instructions closely and be sure to ask any questions you may have about this therapy.

SIDE EFFECTS: Nausea, dizziness, flushing or irritation at the injection site may occur. If these effects persist or worsen, inform your doctor promptly. Notify your doctor if you develop: mouth sores, easy bruising or bleeding, weakness, skin rash, itching, flu-like symptoms (fever, chills), breathing trouble, coughing, vision changes, chest pain, fast heartbeat. This medication affects your blood cells reducing your ability to fight off infections. Notify your doctor if you develop any signs of an infection (fever, chills). If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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