carisoprodol (Soma)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PREPARATIONS: Tablets: 250 and 350 mg.

DRUG INTERACTIONS:

  • Carisoprodol interacts with other medications and drugs that slow the brain's processes, such as alcohol, barbiturates, benzodiazepines (for example, lorazepam [Ativan]), and narcotics, accentuating their effects and causing drowsiness.
  • Omeprazole (Prilosec) and fluvoxamine (Luvox) may reduce the elimination of carisoprodol, leading to increased side effects.
  • St. John's Wort and rifampin (Rifadin) increase the elimination of carisoprodol, possibly resulting in a reduced effect.

PREGNANCY AND BREASTFEEDING SAFETY:

  • There are no adequate studies of carisoprodol in pregnant women.
  • Carisoprodol accumulates in breast milk in concentrations twice those of the mother's blood. The effects of carisoprodol on the infants of lactating mothers are unknown. Therefore, caution should be used when using carisoprodol in women who are breastfeeding.
Medically Reviewed by a Doctor on 7/1/2016

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