carisoprodol, Soma (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

St John's Wort and rifampin (Rifadin) increase the elimination of carisoprodol, possibly resulting in a reduced effect.

PREGNANCY: There are no adequate studies of carisoprodol in pregnant women.

NURSING MOTHERS: Carisoprodol accumulates in breast milk in concentrations twice those of the mother's blood. The effects of carisoprodol on the infants of lactating mothers are unknown. Therefore, caution should be used when using carisoprodol in women who are breastfeeding.

SIDE EFFECTS: Among the most common side effects of carisoprodol are headache, drowsiness, and dizziness. Agitation, nervousness, tremor, irritability, inability to sleep, fainting, abnormal heart beat, seizures, and depression also may occur. Carisoprodol is not a controlled substance. Patients may become dependent on carisoprodol and discontinuation after long-term use may cause withdrawal symptoms.

Reference: FDA Prescribing Information

Last Editorial Review: 3/26/2012

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