captopril, Capoten (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREGNANCY: ACE inhibitors, including captopril, can be harmful to the fetus and should not be taken by pregnant women.

NURSING MOTHERS: Captopril is secreted in breast milk. Therefore it should be avoided by nursing mothers.

SIDE EFFECTS: Captopril generally is well tolerated, and side effects are usually mild and transient. A dry, persistent cough has been reported commonly with the use of captopril and other ACE inhibitors. Coughing resolves after discontinuing the drug. Other side effects include abdominal pain, constipation, diarrhea, rash, dizziness, fatigue, headache, loss of taste, loss of appetite, nausea, vomiting, fainting and numbness or tingling in the hands or feet. Captopril and other ACE inhibitors also may cause kidney failure and increased levels of potassium in the blood. Serious but, fortunately, very rare side effects are liver failure and angioedema (swelling of lips and throat that can obstruct breathing).

Reference: FDA Prescribing Information


Last Editorial Review: 3/12/2009



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