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At high doses, canthaxanthin has caused a serious, potentially fatal blood disorder called aplastic anemia. Canthaxanthin can also cause diarrhea, nausea, stomach cramps, dry and itchy skin, hives, orange or red body secretions, and other side effects.
Special Precautions & Warnings:Pregnancy and breast-feeding: Canthaxanthin is POSSIBLY UNSAFE for pregnant or breast-feeding women when taken by mouth in medicinal amounts to reduce sun sensitivity. It's LIKELY UNSAFE when taken by mouth in amounts needed to produce a tan. It can cause eye damage and other harmful effects.
Vitamin A allergy: People who are allergic to vitamin A and related chemicals called carotenoids might also be sensitive to canthaxanthin.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.