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February 10, 2010
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Canker Sores
(Aphthous Ulcers)

Medical Authors: Siamak Nabili, MD, MPH, and Dennis Lee, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

What are canker sores?

Canker sores are small ulcer craters in the lining of the mouth that are frequently painful and sensitive. Canker sores are very common. About 20% of the population (one out of five people) have canker sores at any one time. Canker sores are also medically known as aphthous ulcers or aphthous stomatitis.

Cankersore (aphthous ulcers) Illustration

Women are slightly more likely than men to have recurrent canker sores. It can occur at any age, but it is more commonly seen in teenagers. Genetic studies show that susceptibility to recurrent outbreaks of the sores is inherited in some patients. This partially explains why family members often share the condition.

Canker sores are generally classified into three groups based on size.

  1. Minor sores have a diameter of 1millimeter (mm) to 10mm. They are the most common (80% of all canker sores) and usually last about 7-10 days.

  2. Major sores (10% of all canker sores) have a diameter of greater than 10mm and they may take anywhere between 10-30 days to heal. They may leave a scar after they heal.

  3. Herpetiform ulcers (10% of all canker sores) are formed by a cluster of multiple small individual sores (less than 3mm). They also usually heal within 7-10 days.

What are symptoms of canker sores?

Canker sores are usually found on the movable parts of the mouth, such as the tongue or the inside lining of the lips and cheeks, and at the base of the gums. The ulcers begin as small oval or round reddish swellings that usually burst within a day. The ruptured sores are covered by a thin white or yellow membrane and edged by a red halo. Generally, the sores heal within two weeks without scarring. Fever is rare, and the sores are rarely associated with other diseases. Usually, a person has only one or a few canker sores at a time.

Most people experience their first bout with canker sores between the ages of 10 and 20. Children as young as 2 years old, however, can develop the condition. The frequency of canker sore recurrences varies considerably. Some people have only one or two episodes a year, while others may have a continuous series of canker sores.



Next: What are the causes of canker sores? »

Canker Sores - Effective Treatments

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Canker Sores

What causes cold sores?

There are two types of HSV, type I and type II. In general, type I, also known as herpes labialis, causes infections above the waist, most commonly as oral "cold sores." Type II infections occur mainly below the waist, leading to genital herpes. However, both types of HSVs are capable of infecting the skin at any location on the body.

Herpes infections, no matter where they occur first, have a tendency to recur in more or less the same place. Such recurrences may happen often (for example, once a month) or only occasionally (for example, once or twice a year).

What makes herpes (cold sores) recur?

After infection, the virus enters the nerve cells and travels up the nerve until it comes to a place called a ganglion. There, it lays quietly in a stage that is referred to as "dormant" or "latent." At times, the virus can start replicating again and travel down the nerve to the skin, causing sores a...

Read the Herpes Simplex Infections (Cold Sores, Non-Genital) article »











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