calcium carbonate, Caltrate 600, Os-Cal 500, Tums Extra, Tums Chewy Delight, and Many Others

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for calcium carbonate?

  • The usual recommended dose of calcium replacement is 1 to 1.2 g given daily in 2 or 4 divided doses with meals.
  • The dose for use as an antacid is 2 to 4 tablets per 24 hours not to exceed 7 g a day.

Which drugs or supplements interact with calcium carbonate?

: Calcium can make it difficult for the body to absorb certain medications. Calcium products bind to quinolone (for example, ciprofloxacin) and tetracycline (for example, Sumycin) antibiotics in the intestine and can prevent their absorption into the body. To prevent this interaction, doses of quinolone and tetracycline antibiotics should be separated by three or more hours from doses of calcium.

Calcium carbonate-containing products reduce acidity in the stomach. The reduction of acid decreases the absorption of iron from the intestine. Therefore, doses of calcium and iron should be separated by a several hours.

Calcium products also bind to sodium polystyrene sulfonate (Kayexalate, a drug used to treat high levels of potassium) in the intestine and, therefore, may interfere with the action of Kayexalate. Doses of Kayexalate and calcium products should be separated by several hours.

Medically Reviewed by a Doctor on 10/25/2016

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