caffeine (Enerjets, No Doz, Vivarin)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

Causes of Fatigue Slideshow Pictures

GENERIC NAME: caffeine (oral)

BRAND NAMES: Enerjets, No Doz, Vivarin

DRUG CLASS AND MECHANISM: Caffeine acts as a stimulant of the nervous system by inhibiting the enzyme phosphodiesterase, just like theophylline and aminophylline. Inhibiting this enzyme leads to increased formation of the proteins which causes release of stimulating chemical signals known as neurotransmitters. These neurotransmitters bind to various sites in the body, including the brain, heart, and muscles to cause a stimulant effect.

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 200 mg; Lozenge: 75mg

STORAGE: Caffeine should be stored at room temperature, between 20 C to 25 C (68 F to 77 F).

PRESCRIBED FOR: Oral caffeine tablets are used to restore mental alertness or wakefulness when experiencing fatigue and drowsiness and caffeine withdrawal.

DOSING: 100 to 200 mg every 3 to 4 hours as needed no later than 6 hours before bedtime.

DRUG INTERACTIONS: Combining caffeine with other stimulating agents, such as methylphenidate (Ritalin, Ritalin SR, Ritalin LA, Concerta, Methylin, Methylin ER, Metadate CD, Metadate ER), should be done with caution. This combination may cause increased side effects including rapid heartbeat, high blood pressure, hallucinations, tremor, and anxiety. Other dietary sources of caffeine, such as tea, add to the effect. Caffeine should be used with caution with adenosine, as the effects of adenosine may be diminished. Linezolid, phenelzine, selegiline, and tranylcypromine combined with caffeine increases the risk of high blood pressure. Consider alternatives when combining caffeine and vemurafenib and Stiripentol as caffeine concentrations may be increased.

Quick GuideSleep Disorders Pictures Slideshow: A Visual Guide to Sleeping Disorders

Sleep Disorders Pictures Slideshow: A Visual Guide to Sleeping Disorders
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Depression Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors