cabergoline, Dostinex (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
DRUG INTERACTIONS: Cabergoline is related to the ergot alkaloids. The use of cabergoline with other ergot alkaloids is not recommended due to the increased risk for adverse events. Ergot alkaloids are commonly used to treat migraine headaches. Therefore, patients receiving treatment for migraine headaches should discuss treatment with cabergoline with their doctor or pharmacist before using cabergoline.
Cabergoline works by stimulating dopamine receptors in the brain. It should not be used with dopamine antagonists or blockers which might decrease or cancel out the beneficial effects of cabergoline. Examples of dopamine antagonists are phenothiazines, butyrophenones, thioxanthenes, and metoclopramide (Reglan).
PREGNANCY: No adequate or well-controlled studies have been conducted in pregnant women. Due to the lack of conclusive safety data, cabergoline should only be used in pregnancy if clearly needed. Cabergoline is classified in FDA pregnancy risk category B.
NURSING MOTHERS: Cabergoline should not be used in breastfeeding mothers because it interferes with the production of breast milk. It is not known whether cabergoline is excreted in human milk.
REFERENCE: FDA Prescribing Information.
Medically Reviewed by a Doctor on 12/10/2014
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