GENERIC NAME: butorphanol
BRAND NAMES: Stadol
DRUG CLASS AND MECHANISM: Butorphanol is a synthetic opioid narcotic pain reliever. It prevents pain in a similar way as morphine (MS Contin), hydrocodone (Zohydro), oxycodone (Oxycontin), and other opioids. Like other opioids, it stimulates receptors in the brain to increase the threshold to pain (the amount of stimulation it takes to feel pain) and reduce the perception of pain (the perceived importance of the pain). The FDA approved butorphanol in August 1978.
GENERIC AVAILABLE: Yes
PREPARATIONS: Solution with or without preservatives: 1 or 2 mg/mL in 1, 2, 10 mL; Nasal solution: 10 mg/ mL in 2.5 mL bottle.
STORAGE: Butorphanol solution should be stored at room temperature, between 15 C to 30 C (59 F to 86 F) and protected from light. Nasal spray should be stored at room temperature between 20 C to 25 C (68 F to 77 F).
PRESCRIBED FOR: Butorphanol is prescribed for the treatment of pain that is severe enough to require an opioid, as well as for preoperative or preanesthetic pain management. It is also used to supplement balanced anesthesia and manage pain during labor.
DOSING: The initial dose for adults is based on the setting in which it is used, as well as whether it is delivered intramuscularly, intravenously, or through nasal spray. Most initial intravenous doses for pain range between 0.5 to 2 mg, which may be repeated every 3 to 4 hours as needed.
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