busulfan-oral (cont.)
SIDE EFFECTS: Nausea, diarrhea or constipation, headache, skin darkening, or flushing may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Tell your doctor immediately if any of these serious side effects occur: unusual tiredness, fast or irregular heartbeat, fever, persistent sore throat, easy bruising/bleeding, mental/mood changes, increased thirst, blurred vision, muscle cramps or weakness, chest pain, seizures, sudden weight gain or loss, stomach pain or swelling, change in amount or color of urine, mouth sores. Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, fainting, vomiting. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: dark urine, yellowing eyes/skin, coughing up blood, vision problems. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. Rare, possibly fatal, lung problems may occur months to years after using busulfan. Symptoms include trouble breathing or persistent cough or congestion. Report any symptoms promptly. If your leukemia symptoms reoccur or worsen, notify your doctor immediately. Busulfan itself may infrequently cause cancer. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially: seizures, head injury, blood disorders (e.g., low blood counts, or thalassemia), diabetes, lung disease, any serious infections, any allergies. Because this medication can lower your body's ability to fight an infection, do not touch your eyes or the inside of your nose without first washing your hands. Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine. Use caution with sharp objects like safety razors or nail cutters, and avoid activities that might cause injury. Caution is advised when using this drug in children because they may clear the drug from their system faster, and therefore may require special dosing and monitoring. This drug may also cause fertility problems. This medication is not recommended for use during pregnancy. Busulfan may cause fetal harm. Avoid becoming pregnant while using this drug. Consult your doctor for more details. It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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