bupropion hydrochloride extended release (Forfivo XL)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Understanding Depression Slideshow

PRESCRIBED FOR: Bupropion is used for the management of major depression.

SIDE EFFECTS: The most common side effects associated with bupropion are:

In some people, the agitation or insomnia is most marked shortly after starting therapy. Some patients may experience weight loss. Uncommonly, patients may experience manic episodes or hallucinations. Four of every 1000 persons who receive bupropion in doses less than 450 mg/day experience seizures. When doses exceed 450 mg/day, the risk increases ten-fold. Other risk factors for seizures include past injury to the head and medications which can lower the threshold for seizures. (See drug interactions.)

Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Forfivo or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidality, or unusual changes in behavior.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes (other extended release formulations of bupropion)

PREPARATIONS:

  • Tablets: 75, 100, and 150 mg.
  • Sustained Release tablets: 100, 150 and 200 mg.
  • Extended Release tablets: 150 and 300 mg.

STORAGE: Tablets should be kept at room temperature, 15 C to 25 C (59 F to 77 F).

Medically Reviewed by a Doctor on 12/22/2015

Quick GuideDepression Hurts: Physical Symptoms of Depression

Depression Hurts: Physical Symptoms of Depression
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