BUPROPION-ORAL (cont.)
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: MAO inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline, linezolid, furazolidone). If you are currently using or have recently stopped taking an MAO inhibitor within the last 14 days, tell your doctor or pharmacist before starting bupropion. Before taking this medicine, tell your doctor of all nonprescription and prescription medications you may use especially: levodopa, warfarin, ritonavir, adrenaline-like stimulants (e.g., ephedrine), regular use of sedatives (e.g., diazepam), diabetes medications (e.g., hypoglycemic agents such as glyburide, glipizide, or insulin), amantadine, products containing nicotine (e.g., patches or gum). Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with bupropion such as phenothiazines (e.g., thioridazine), tricyclic antidepressants (e.g., amitriptyline), isoniazid (INH), or theophylline among others. Consult your doctor or pharmacist for details. Excess caffeine intake can increase the chance of seizures with this drug. Check all nonprescription/prescription drug labels for caffeine. Consult your doctor or pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include seizures, hallucinations, rapid heart rate, and loss of consciousness.
NOTES: Do not allow anyone else to take this medication.
MISSED DOSE: Take any missed dose as soon as possible but not if it is within 4 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.
STORAGE: Store at room temperature and keep away from moisture and sunlight. Do not store in the bathroom.
Last Editorial Review: 3/2/2005
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