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PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: lung disease, liver disease, serious head injury or brain diseases (lesions), low thyroid problems (hypothyroidism), adrenal problems (Addison's disease), psychiatric problems (toxic psychosis), difficulty urinating (enlarged prostate or urethral narrowing), acute alcoholism (with or without delirium tremens), spinal problems (kyphoscoliosis), gallbladder (biliary tract) disease and other abdominal conditions.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially the possible decreased breathing and drowsiness effects.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.This drug passes into breast milk. Due to the potential risk to the infant, breast-feeding while using this drug is not recommended.

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, isocarboxazid, tranylcypromine), drugs which decrease liver metabolism (inhibitors of cytochrome 3A4 enzymes such as itraconazole, ketoconazole, erythromycin, clarithromycin, ritonavir, indinavir, saquinavir), local anesthetics (e.g., bupivacaine), sedative drugs (benzodiazepines such as diazepam, lorazepam).Deaths have occurred when buprenorphine/naloxone has been misused, especially when used in combination with benzodiazepines (e.g., diazepam, lorazepam) or other depressants such as alcohol or additional narcotics.Also report the use of other drugs that cause drowsiness such as: medicine for sleep (e.g., sedatives), tranquilizers, anti-anxiety drugs (e.g., temazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline), anti-seizure drugs (e.g., carbamazepine), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Report Problems to the Food and Drug Administration   You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.