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buprenorphine/naloxone - sublingual, Suboxone (cont.)

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, isocarboxazid, tranylcypromine), drugs which decrease liver metabolism (inhibitors of cytochrome 3A4 enzymes such as itraconazole, ketoconazole, erythromycin, clarithromycin, ritonavir, indinavir, saquinavir), local anesthetics (e.g., bupivacaine), sedative drugs (benzodiazepines such as diazepam, lorazepam).Deaths have occurred when buprenorphine/naloxone has been misused, especially when used in combination with benzodiazepines (e.g., diazepam, lorazepam) or other depressants such as alcohol or additional narcotics.Also report the use of other drugs that cause drowsiness such as: medicine for sleep (e.g., sedatives), tranquilizers, anti-anxiety drugs (e.g., temazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline), anti-seizure drugs (e.g., carbamazepine), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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