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March 14, 2010
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Bullous Pemphigoid (cont.)

How is bullous pemphigoid treated?

Bullous pemphigoid can be chronic and mild without affecting the general health of affected individuals. Treatment of bullous pemphigoid can resolve with topical cortisone creams but sometimes requires high doses of cortisone ("steroids") taken internally. Severe bullous pemphigoid can also require immune-suppression drugs such as azathioprine (Imuran). Tetracycline has been used as a treatment option. Other treatments that have been used for severe disease include intravenous immunoglobulin infusions, typically given monthly.

Recent research has indicated that large quantities of high-potency topical corticosteroids applied to the entire body surface were safer and more effective in controlling extensive bullous pemphigoid than oral corticosteroids. It was felt by the researchers that topical corticosteroids should now be the treatment of choice for bullous pemphigoid, particularly when the disease is not extensive.


Last Editorial Review: 1/25/2008




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