budesonide/formoterol (4.5 micrograms) hfa inhaler - oral, Symbicort (cont.)

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medication because very serious interactions may occur: natalizumab.If you are currently using the medication listed above, tell your doctor or pharmacist before starting this product.Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, and 2 weeks after treatment with this medication. In some cases a serious, possibly fatal drug interaction may occur.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adrenaline-like drugs (e.g., phenylephrine, pseudoephedrine), aldesleukin, amphotericin B, other asthma drugs (e.g., quick-relief inhalers, theophylline), beta blockers (e.g., propranolol, sotalol), corticosteroids taken by mouth (e.g., dexamethasone, prednisone), drugs affecting liver enzymes that remove budesonide from your body (e.g., azole antifungals including ketoconazole; macrolide antibiotics including erythromycin; cimetidine; rifamycins including rifampin; St. John's wort; certain anti-seizure medicines including carbamazepine), inhaled anesthetics (e.g., halothane), mifepristone, tricyclic antidepressants (e.g., amitriptyline, nortriptyline).Many drugs besides this product may affect the heart rhythm (QT prolongation in the EKG), including amiodarone, dofetilide, pimozide, quinidine, sotalol, ranolazine, sparfloxacin, procainamide, macrolide antibiotics (such as erythromycin), among others. Therefore, before using budesonide/formoterol, report all medications you are currently using to your doctor or pharmacist.Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about using those products safely.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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