- What is BUDESONIDE/FORMOTEROL-INHALATION, and how does it work (mechanism of action)?
- What brand names are available for BUDESONIDE/FORMOTEROL-INHALATION?
- Is BUDESONIDE/FORMOTEROL-INHALATION available as a generic drug?
- Do I need a prescription for BUDESONIDE/FORMOTEROL-INHALATION?
- What are the side effects of BUDESONIDE/FORMOTEROL-INHALATION?
- What is the dosage for BUDESONIDE/FORMOTEROL-INHALATION?
- Which drugs or supplements interact with BUDESONIDE/FORMOTEROL-INHALATION?
- Is BUDESONIDE/FORMOTEROL-INHALATION safe to take if I'm pregnant or breastfeeding?
- What else should I know about BUDESONIDE/FORMOTEROL-INHALATION?
What is the dosage for BUDESONIDE/FORMOTEROL-INHALATION?
The recommended dose is 2 inhalations twice daily of 80 mcg/4.5 mcg or 160 mcg/5 mcg strengths. The dose for treating COPD is 2 inhalations of 160/4.5 strength twice daily.
Which drugs or supplements interact with BUDESONIDE/FORMOTEROL-INHALATION?
The following drugs may increase levels of budesonide in the body by reducing the breakdown of budesonide byliver enzymes. This may increase side effects of Symbicort.
- ritonavir (Norvir),
- atazanavir (Reyataz),
- clarithromycin (Biaxin),
- indinavir (Crixivan),
- itraconazole (Sporanox),
- nelfinavir (Viracept), and
- telithromycin (Ketek)
Monoamine oxidase inhibitors (for example, tranylcypromine) and tricyclic antidepressants (for example, amitriptyline [Endep]) may increase the effect of formoterol on the heart and blood pressure. Since Symbicort contains formoterol, it should not be used with or within two weeks of discontinuing monoamine oxidase inhibitors or tricyclic antidepressants.
Beta blockers block the therapeutic effects of beta 2-agonists, such as formoterol, a component of Symbicort, and may produce severe bronchospasm in patients with asthma. Therefore, patients with asthma should not be treated with beta- blockers.
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