budesonide, Entocort EC, Uceris extended release tablets (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: Yes
PREPARATIONS: Capsules: 3 mg; Tablets (Extended Release): 9 mg
STORAGE: Capsules should be stored between 15C to 30 C (59 F to 86 F)
PRESCRIBED FOR: Budesonide is used for the treatment of mild-to-moderately-active Crohn's disease involving the ileum (the second half of the small intestine) and/or ascending colon (the beginning of the large intestine). It is approved for maintaining remissions for up to three months. It is also used for induction of remission in patients with active, mild to moderate ulcerative colitis.
DOSING: The recommended dose for active Crohn's disease is 9 mg once daily in the morning for up to 8 weeks. The 8 week course may be repeated for recurring episodes. The dose for maintenance of remission is 6 mg once daily for 3 months. The recommended dosage for the induction of remission in adult patients with active, mild to moderate ulcerative colitis is one 9 mg extended release tablet to be taken once daily in the morning for up to 8 weeks.
DRUG INTERACTIONS: Medicines which block the liver enzymes that break down budesonide may lead to higher blood concentrations and more side effects of budesonide. Such medications include ketoconazole (Nizoral), fluconazole (Diflucan), itraconazole (Sporanox), clarithromycin (Biaxin), erythromycin, verapamil (for example, Calan; Isoptin; Covera HS), diltiazem (for example, Cardizem; Dilacor), ritonavir (Norvir; Kaletra), indinavir (Crixivan), and saquinavir (Invirase, Fortovase). Grapefruit juice has a similar effect and should not be consumed by patients taking budesonide.
Medically Reviewed by a Doctor on 11/11/2013
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