brimonidine, (Alphagan, Alphagan P - Discontinued in the US)

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Medical and Pharmacy Editor:

GENERIC NAME: brimonidine

BRAND NAME: Alphagan P

DRUG CLASS AND MECHANISM: Brimonidine is is an ophthalmic solution used for the treatment of one type of glaucoma, open-angle glaucoma. In this type of glaucoma, too much fluid (aqueous humor) is made within the eye and causes high pressures within the eye. The pressure damages the nerves in the eye responsible for vision, and this ultimately causes blindness. Brimonidine reduces the body's production of aqueous humor and increases the flow of aqueous humor out of the eye, resulting in a decrease in pressure. It accomplishes this by stimulating alpha type 2 receptors selectively in the eye with less effect on alpha type 2 receptors elsewhere in the body. It is the first drug of its class to be used for glaucoma. Brimonidine was approved by the FDA in 1996.

PRESCRIBED FOR: Brimonidine is used for the reduction of intraocular pressure in patients with open-angle glaucoma.

Medically Reviewed by a Doctor on 4/6/2015

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