bretylium tosylate-injection (cont.)

SIDE EFFECTS: Dizziness, nausea, vomiting or pain/redness at the injection site may occur. If these effects persist or worsen, notify the doctor. Very unlikely but report promptly: slow or irregular heartbeat, fainting, headache, chest pain, change in amount of urine, rash, mental/mood changes, fever, sweating, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell the doctor the patient's medical history, including: any allergies, kidney disease, heart disease, blocked blood vessels (aortic stenosis), lung problems (pulmonary hypertension). To avoid dizziness and lightheadedness, the patient should remain lying down or, if necessary, get up slowly when rising from a seated or lying position. Caution is advised when using this drug in the elderly since they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with the doctor. It is not known whether this drug is excreted into breast milk. Consult the doctor before breast-feeding.

DRUG INTERACTIONS: Tell the doctor of all nonprescription and prescription medication the patient uses, especially of: digoxin, catecholamines (e.g., dopamine or norepinephrine), other heart rhythm medications (e.g., quinidine, procainamide, propranolol). Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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