Botulism (cont.)

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What specialists treat botulism?

In addition to the patient's primary-care physician, other physicians may be appropriate to consult; for example, for hospitalized patients, a critical-care specialist, neurologist, infectious-disease specialist, and a pediatric specialist if a child or infant has the disease.

What are complications from botulism?

Botulism can result in death from respiratory failure. In the past 50 years, the rate of death from botulism has fallen significantly. Unfortunately, a patient with severe botulism may require not only a breathing machine for ventilation but also intensive medical and nursing care for several months to survive.

Patients who survive an episode of botulism poisoning may experience fatigue and shortness of breath for years, and long-term therapy may be needed to aid recovery.

In 2009, the FDA increased its label precautions on the three available products: Botox, Dysport, and Myobloc. All three are different formulations of the toxin and are not interchangeable with regard to dosing. In addition, the FDA cautions that all the symptoms of botulism can occur if the treatments are inappropriately given, especially in high doses or if some of the solution seeps out of the localized area where it is injected. The FDA further warned health-care professionals that suppliers of medical toxins that do not have FDA approval may supply faulty products that could harm individuals.

What is the prognosis (outcome) of people with botulism?

Untreated botulism has a mortality rate (death rate) of about 50%. Appropriately treated patients with botulism currently still have a mortality rate of about 3%-5%. Some patients may experience various degrees of paralysis for many months. In general, the earlier the diagnosis and treatment of the disease, the better is the prognosis. However, outcomes may be considered only fair in some patients who develop chronic fatigue and shortness of breath for many years after the initial diagnosis and treatment of botulism.

Medically Reviewed by a Doctor on 11/16/2015

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