Multiple Sclerosis: Botox Treatment

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What is Botox?

Botox is one specific brand of purified botulinum toxin, which is the toxin produced by the bacterium Clostridium botulinum. Medical uses of botulinum toxin began in 1980, when targeted weakening of eye muscles was identified as a potential treatment of strabismus, a condition in which the eyes don't line up correctly.

Although many different types of botulinum toxin have been identified, only types A and B are approved for the use in treatment of muscle problems. In addition to Botox, other approved forms of botulinum toxin A include Dysport and Xeomin. Myobloc is the approved form of botulinum toxin B.

When used for clinical purposes, the toxin is used in small amounts, leading to weakness in the muscles into which it is injected. This weakness can be beneficial in various conditions characterized by too much muscle activity, such as dystonia or spasticity. This is in distinct contrast to the disease botulism, which occurs when the non-purified bacterium is ingested and the toxin is dispersed through the body causing widespread weakness.

What is multiple sclerosis?

Multiple Sclerosis (MS) is a disease that causes demyelination of the brain and spinal cord. When this occurs, axons (the parts of the nerve cells that conduct impulses to other cells) don't work well. As more areas are affected by this loss of myelin, patients develop symptoms. The specific symptom that someone might experience is related to the area of injury in the brain or spinal cord. Patients might describe numbness, tingling, or weakness. The weakness may be mild or severe enough to cause paralysis of one side of the body. In some cases, patients may develop incontinence or even an inability to empty their bladder. As multiple sclerosis progresses, some patients are left with muscle spasticity or an involuntary painful contraction of certain muscles.

Medically Reviewed by a Doctor on 4/30/2014

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Botox for MS - Spasticity Question: Have you used Botox for multiple sclerosis spasticity? Did it work?
Botox for MS - Treatment Question: Have you used Botox as part of your multiple sclerosis treatment?
Botox for MS - Injections Question: How many injections do you get for each Botox treatment for your multiple sclerosis symptoms?