bortezomib-injection (cont.)
PRECAUTIONS: Before using this medication, tell your doctor or pharmacist your medical history, especially of: nerve sensation problems (e.g., peripheral neuropathy), low blood pressure, loss of body fluids (dehydration), diabetes, liver disease, severe kidney disease, any allergies (especially to boron or mannitol). To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. This drug may make you dizzy or cause vision changes; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Do not have immunizations/vaccinations without the consent of your doctor and avoid contact with people who have recently received oral polio vaccine. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured. Wash your hands well to prevent the spread of infections. This medication must not be used during pregnancy. It may cause fetal harm. If you become pregnant or think you may be pregnant, inform your doctor immediately. Use reliable form(s) of birth control during treatment with this drug. Consult your doctor for more details. It is not known whether this drug passes into breast milk. Breast-feeding is not recommended while using this drug due to the potential risk to the nursing infant. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: medications to treat high blood pressure, oral anti-diabetic drugs, other drugs that may cause peripheral neuropathy (e.g., amiodarone, isoniazid, nitrofurantoin, certain anti-virals such as acyclovir, ritonavir, zidovudine). Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: fainting or persistent fever.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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