boceprevir (Victrelis)

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GENERIC NAME: boceprevir

BRAND NAME: Victrelis

DRUG CLASS AND MECHANISM: Boceprevir is a man-made antiviral medication that targets hepatitis C virus (HCV). Similar drugs include simeprevir (Olysio) and telaprevir (Incivek). These drugs are called direct-acting antiviral agents because they act directly on hepatitis C virus. They block the replication of hepatitis C virus in human cells by binding to and inhibiting protease enzymes that HCV use for reproducing. Inhibiting viral replication reduces HCV viral load in the body to undetectable levels in some patients. The FDA approved boceprevir in March 2011.



PREPARATIONS: Capsule, 200 mg

STORAGE: Boceprevir should be refrigerated at 2 C to 8 C (36 F 46 F) until dispensed. Refrigerated boceprevir can remain stable until the expiration date. Boceprevir can also be stored at room temperature up to 25 C (77 F) for 3 months. Boceprevir should be stored in tightly closed containers, avoiding exposure to excessive heat.

PRESCRIBED FOR: Boceprevir is used for chronic hepatitis C genotype 1 infection, in combination with peginterferon alfa and ribavirin (Rebetol, Copegus) in adults with compensated liver disease who have not been treated before or failed previous treatment.

Medically Reviewed by a Doctor on 7/18/2014

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