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What are the symptoms and signs of bocavirus infection?
Because bocavirus is usually only found in individuals (usually infants, children, and infrequently in young adults) with lower respiratory infections or diarrhea, these are the following symptoms and signs associated with the presence of bocavirus:
- ARTI (also termed RTIs, acute respiratory tract infections), especially in infants and children
- Cyanosis (bluish or grayish tint to skin due to lack of oxygen)
- Rhinorrhea (runny nose)
The infants and children with these nonspecific symptoms often are very ill and require hospitalization. It is important to note that it is not clear yet that bocavirus is either completely or partially responsible for these signs and symptoms. Currently, most of the clinical articles that discuss bocavirus describe patients with at least several of the symptoms and signs listed above, with pneumonia as the major problem. Some investigators report months of bocavirus shedding (having tests demonstrate the presence of the virus in body secretions) in patients with cancer (leukemia), but the significance of this shedding is not clear.