GENERIC NAME: bitolterol mesylate

BRAND NAME: Tornalate

DRUG CLASS AND MECHANISM: Tornalate is a bronchodilator used in the treatment of asthma and other conditions with reversible airway problems (e.g. emphysema and chronic bronchitis).

Asthma is a breathing involving narrowing of the bronchial tubes. This narrowing is caused by muscle spasm and inflammation within the bronchial tubes. Tornalate relaxes the smooth muscles surrounding these airway tubes, therefore, increases the diameter and ease of air flow through the tubes. Tornalate probably does not affect the inflammation in the lung, such as in bronchitis. Tornalate is unique in that it is a "prodrug" because it must first be metabolized by the body before it becomes active.

PRESCRIPTION: yes

GENERIC AVAILABLE: no

PREPARATIONS: Metered dose inhaler in 16.4 grams (15ml) and a 10ml dropper bottles containing 0.2% solution for hand held nebulizer.

STORAGE: Store in a dry place at 15-30 degrees C (59-86 F)

PRESCRIBED FOR: Tornalate is used for the relief of bronchospasms as is found in asthma and some other respiratory illnesses. Tornalate has a rapid onset of action (2-5 minutes) and may last up to 6-8 hours.

DOSING: Tornalate should be taken at doses specifically directed by your physician. Overuse can lead to asthma and other complications, including heart irregularities. Proper technique using the inhaler is important. Consult your pharmacist or physician to show you how to use the inhaler properly. Do not mix with Intal (cromolyn) in the same vial.

DRUG INTERACTIONS: Tornalate should be used with caution in persons with heart disease especially if they have arrhythmias. One should be cautious of concurrent use with tricyclic antidepressants, such as ELAVIL. Lowering of potassium has been reported. This product contains alcohol and when inhaled can give elevated alcohol breath analysis.

SIDE EFFECTS: Tremors are the most common side effect. Palpitations, fast heart rate, elevated blood pressure, nausea, and dizziness occasionally occur. Throat irritation and unpleasant taste also occurs.

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From the Doctors at MedicineNet.com

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Last Editorial Review: 12/31/1997