GENERIC NAME: bitolterol mesylate
BRAND NAME: Tornalate
DRUG CLASS AND MECHANISM: Tornalate is a bronchodilator
used in
the treatment of asthma and other conditions with reversible
airway
problems (e.g. emphysema and chronic bronchitis).
Asthma is a breathing involving narrowing of the bronchial
tubes. This
narrowing is caused by muscle spasm and inflammation within the
bronchial
tubes. Tornalate relaxes the smooth muscles surrounding these
airway
tubes, therefore, increases the diameter and ease of air flow
through the
tubes. Tornalate probably does not affect the inflammation in
the lung,
such as in bronchitis. Tornalate is unique in that it is a
"prodrug"
because it must first be metabolized by the body before it
becomes active.
PRESCRIPTION: yes
GENERIC AVAILABLE: no
PREPARATIONS: Metered dose inhaler in 16.4 grams (15ml)
and a
10ml dropper bottles containing 0.2% solution for hand held
nebulizer.
STORAGE: Store in a dry place at 15-30 degrees C (59-86
F)
PRESCRIBED FOR: Tornalate is used for the relief of
bronchospasms as is found in asthma and some other respiratory
illnesses.
Tornalate has a rapid onset of action (2-5 minutes) and may
last up to 6-8
hours.
DOSING: Tornalate should be taken at doses specifically
directed
by your physician. Overuse can lead to asthma and other
complications,
including heart irregularities. Proper technique using the
inhaler is
important. Consult your pharmacist or physician to show you how
to use the
inhaler properly. Do not mix with Intal (cromolyn) in the same
vial.
DRUG INTERACTIONS: Tornalate should be used with
caution in
persons with heart disease especially if they have arrhythmias.
One should
be cautious of concurrent use with tricyclic antidepressants,
such as
ELAVIL. Lowering of potassium has been reported. This product
contains
alcohol and when inhaled can give elevated alcohol breath
analysis.
SIDE EFFECTS: Tremors are the most common side effect.
Palpitations, fast heart rate, elevated blood pressure, nausea,
and
dizziness occasionally occur. Throat irritation and unpleasant
taste also
occurs.
Last Editorial Review: 12/31/1997
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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