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February 8, 2012

bisoprolol and hydrochlorothiazide, Ziac

GENERIC NAME: bisoprolol and hydrochlorothiazide

BRAND NAME: Ziac

DRUG CLASS AND MECHANISM: Ziac is a combination product containing: bisoprolol (Zebeta) and hydrochlorothiazide (Esidrix; Oretic).

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 2.5mg bisoprolol/6.25mg hydrochlorothiazide, 5mg bisoprolol/6.25mg hydrochlorothiazide, 10mg bisoprolol/6.25mg hydrochlorothiazide.

STORAGE: Ziac should be stored at room temperature, 59- 86°F (15-30°C) in a tight container.

PRESCRIBED FOR: Ziac is used for treating patients with high blood pressure.

DOSING: The dose of Ziac is tailored to the patient's needs.

DRUG INTERACTIONS: Please see the individual drugs' articles for bisoprolol (Zebeta) and hydrochlorothiazide (Esidrix; Oretic).

PREGNANCY: There is no information about the effects of ZIAC on the fetus in pregnant women. Physicians may elect to use Ziac if its benefits are deemed to outweigh potential risks.

NURSING MOTHERS: Please see the individual drugs' articles for bisoprolol (Zebeta) and hydrochlorothiazide (Esidrix; Oretic).

SIDE EFFECTS: Please see the individual drugs' articles for bisoprolol (Zebeta) and hydrochlorothiazide (Esidrix; Oretic). Since the dose of hydrochlorothiazide in Ziac is low, the risk of a reduced level of potassium in the blood is no greater than with placebo.

Reference: FDA Prescribing Information


Last Editorial Review: 12/31/1997




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bisoprolol and hydrochlorothiazide, Ziac

What is high blood pressure?

High blood pressure (HBP) or hypertension means high pressure (tension) in the arteries. Arteries are vessels that carry blood from the pumping heart to all the tissues and organs of the body. High blood pressure does not mean excessive emotional tension, although emotional tension and stress can temporarily increase blood pressure. Normal blood pressure is below 120/80; blood pressure between 120/80 and 139/89 is called "pre-hypertension", and a blood pressure of 140/90 or above is considered high.

The top number, the systolic blood pressure, corresponds to the pressure in the arteries as the heart contracts and pumps blood forward into the arteries. The bottom number, the diastolic pressure, represents the pressure in the arteries as the heart relaxes after the contraction. The diastolic pressure reflects the lowest pressure to which the arteries are exposed.

An elevation of the systolic and/or diastolic blood pressure increas...

Read the High Blood Pressure article »







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