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February 10, 2012

Bird Flu (cont.)

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What are risk factors for bird flu?

Humans may get bird flu from contact with infected birds (chickens, for example) or their droppings or surfaces with infected droppings. Risk factors include caring for sick birds, killing sick birds, and preparing sick birds for consumption. Despite the large number of people who have contact with poultry every day in the world, human cases of bird flu remain rare. This highlights how difficult it is for the bird flu virus to infect human cells, but mutations like antigenic shifts may reduce such difficulties.

Although direct contact with sick poultry poses the highest risk, indirect exposure to bird feces is also a risk. Thus, contact with unwashed eggs from sick birds or water contaminated by poultry feces poses a potential risk of disease.

Human to human spread has occurred in isolated cases. Thus, caring for a person infected with bird flu is also a risk factor for the disease. There is a theoretical risk in laboratory workers who handle the avian flu virus. One alleged incident in 2009 occurred when a company inadvertently sent live avian flu virus samples to research laboratories, which subsequently were used to vaccinate ferrets. The contaminated vaccine did not result in any human cases of infection.

What are bird flu symptoms and signs?

Symptoms occur approximately two to eight days after exposure, on average. Infected people experience typical flu-like symptoms, including fever, cough, sore throat, and muscle aches. Some people also have nausea, vomiting, diarrhea, or eye infections. This can progress to pneumonia and even respiratory failure. Bird flu causes a very aggressive form of pneumonia (acute respiratory distress syndrome or ARDS) that is often fatal.



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