Biological TherapyWhat is biological therapy? How does biological therapy work? Biological therapy often involves the use of substances called biological response modifiers (BRMs). The body normally produces these substances in small amounts in response to infection and disease. Using modern laboratory techniques, scientists can produce BRMs in large amounts for use in the treatment of cancer and other diseases, such as rheumatoid arthritis and Crohn's disease. What are examples of biological therapies? Modes of biologic therapy that involve blocking the action of specific proteins of inflammation, called tumor necrosis factor (TNF), are being used for the treatment of a number of diseases, including rheumatoid arthritis and Crohn's disease. Etanercept (Enbrel) and infliximab (Remicade) are examples of commercially available injectable TNF-blocking treatments for patients with severe rheumatoid arthritis. |
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Related Diseases & Conditions
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Rheumatoid Arthritis
- Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease.
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Crohn's Disease
- Crohn's disease is a chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. Abdominal pain, diarrhea, vomiting, fever, and weight loss are common symptoms.
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Melanoma
- Melanoma is a type of skin cancer which begins in skin cells called melanocytes and affects more than 53,600 people in the United States each year. These melanocytes can grow together to form benign moles which, after a change in size, shape, or color can be a sign of melanoma. Caused by sun exposure, early detection becomes extremely important to avoid a spread to other areas of the body. Diagnosis is confirmed through a biopsy of the abnormal skin and treatment depends on the extent and characteristics of the patient.
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Kidney Cancer
- There are several types of kidney cancer, including renal cell cancer (renal adenocarcinoma or hypernephroma), transitional cell carcinoma, and Wilms tumor. Symptoms of kidney cancer include blood in the urine, an abdominal lump or mass, chronic pain in the side, and tiredness. Treatment of kidney cancer--which may include surgery, arterial embolization, radiation therapy, biological therapy or chemotherapy--depends upon the stage of the disease and the patient's overall health.
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Bladder Cancer
- Treatment for bladder cancer depends on the stage of the disease, the grade of the tumor, and the type of bladder cancer. Options for treatment include surgery, radiation therapy, chemotherapy, and biological therapy.
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Non-Hodgkin's Lymphoma
- Non-Hodgkin's lymphoma is cancer of the lymphatic system, a vital part of the body's immune system. Symptoms include swollen lymph nodes, fever, night sweats, coughing, weakness, chest pain, unexplained weight loss, and abdominal pain. Treatment depends on which type of non-Hodgkin's lymphoma you have, the stage of the cancer, your age, how fast the cancer is growing, and whether you have other health problems.
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Penis Cancer
- Signs and symptoms of penile cancer include a lump on the penis and redness, irritation, or a sore on the penis. Risk of penis cancer is higher in uncircumcised men, due to a higher risk of HPV infection. Other risk factors include being over 60, having phimosis, having poor hygiene, using tobacco products, and having many sex partners. Prognosis and treatment depend upon the tumor's location and size, the stage of the cancer, and whether the cancer was recently diagnosed or if it recurred.
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Head and Neck Cancer
- Head and neck cancer is cancer of the oral cavity, salivary glands, paranasal sinuses and nasal cavity, pharynx, larynx, or lymph nodes in the upper part of the neck. These cancers account for 3% to 5% of cancers in the U.S. Tobacco and alcohol use are important risk factors. Treatment may involve surgery, radiation therapy, and/or chemotherapy.
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Nasopharyngeal Cancer
- Nasopharyngeal cancer is a form of cancer in which malignant cells form in the nasopharynx tissues. Risk factors include being of Chinese or Asian ancestry and exposure to the Epstein-Barr virus. Symptoms and signs of nasopharyngeal cancer include a sore throat, a lump in the neck or nose, trouble hearing, nosebleeds, headaches, and trouble hearing, breathing, or speaking. Treatment depends upon the stage of the cancer, the tumor size, the type of cancer, and the patient's health and age.
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Rheumatoid Arthritis
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