Binswanger's Disease (cont.)

How is Binswanger's disease diagnosed?

Brain imaging, which reveals the characteristic brain lesions of Binswanger's disease, is essential for a positive diagnosis.

Is there any treatment for Binswanger's disease?

There is no specific course of treatment for Binswanger's disease. Treatment is symptomatic.

  • People with depression or anxiety may require antidepressant medications such as the serotonin-specific reuptake inhibitors (SSRI) sertraline or citalopram.

  • Atypical antipsychotic drugs, such as risperidone and olanzapine, can be useful in individuals with agitation and disruptive behavior.

  • Recent drug trials with the drug memantine have shown improved cognition and stabilization of global functioning and behavior.

  • The successful management of hypertension and diabetes can slow the progression of atherosclerosis, and subsequently slow the progress of Binswanger's disease.

  • Because there is no cure, the best treatment is preventive, early in the adult years, by controlling risk factors such as hypertension, diabetes, and smoking.

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