bimatoprost, Latisse, Lumigan
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: bimatoprost
BRAND NAME: Latisse, Lumigan
DRUG CLASS AND MECHANISM: Bimatoprost is a synthetic (man-made) drug that resembles and mimics the effects of natural chemicals (prostaglandins) produced by the body. It is used for reducing intraocular pressure (IOP) and increasing the growth of eyelashes. The exact mechanism of action is unknown. Bimatoprost may reduce IOP by increasing the outflow of aqueous humor from the eye of individuals with narrow angle glaucoma. Excessive aqueous humor may cause optic nerve damage and visual loss. It may increase eyelash growth by increasing the duration of the growing phase of the eyelash. The FDA approved Lumigan in March 2001 and Latisse in December 2008.
GENERIC AVAILABLE: No
PREPARATIONS: Solution (eye drops): 0.03 mg/ml
STORAGE: Solutions should be store at 2-25 C (36-77 F).
PRESCRIBED FOR: Bimatoprost is used for reducing IOP in individuals with narrow angle glaucoma or ocular hypertension. It also is used for increasing thickness, length, and darkness of eyelashes.
DOSING: The recommended dosage of bimatoprost for reducing IOP is one drop in the affected eye(s) once daily in the evening. More frequent administration may reduce the IOP-reducing effect. Reduction in IOP starts approximately four hours after administration and maximum effect occurs in approximately 8 to 12 hours. The recommended regimen for increasing eyelash growth is one drop applied with an applicator evenly along the skin of the upper eyelid at the base of the eyelashes of each eye every evening.
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