bicalutamide, Casodex (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Other common side effects of the combination are:

LHRH analogs may increase blood glucose and worsen diabetes. Less common side effects are breast enlargement and breast pain, which may be due to the bicalutamide alone.



PREPARATIONS: Tablet: 50 mg.

STORAGE: Bicalutamide should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

DOSING: Bicalutamide should be taken as one 50 mg tablet in the morning or evening at the same time each day. It may be taken with or without food. Once bicalutamide therapy has begun, it should not be interrupted or stopped without consulting a physician.

DRUG INTERACTIONS: Bicalutamide may interact with warfarin (Coumadin). Therefore, the dose of warfarin may need to be adjusted, and the ability of blood to clot should be closely monitored.

Bicalutamide reduces the activity of liver enzymes that breakdown certain drugs, for example, midazolam (Versed). Such combinations should be avoided if possible.

PREGNANCY: Bicalutamide is not used for treating women.

NURSING MOTHERS: Bicalutamide is not used for treating women.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 4/6/2015

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