bicalutamide, Casodex

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Cancer 101: Cancer Explained

Other common side effects of the combination are:

LHRH analogs may increase blood glucose and worsen diabetes. Less common side effects are breast enlargement and breast pain, which may be due to the bicalutamide alone.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Tablet: 50 mg.

STORAGE: Bicalutamide should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

DOSING: Bicalutamide should be taken as one 50 mg tablet in the morning or evening at the same time each day. It may be taken with or without food. Once bicalutamide therapy has begun, it should not be interrupted or stopped without consulting a physician.

DRUG INTERACTIONS: Bicalutamide may interact with warfarin (Coumadin). Therefore, the dose of warfarin may need to be adjusted, and the ability of blood to clot should be closely monitored.

Bicalutamide reduces the activity of liver enzymes that breakdown certain drugs, for example, midazolam (Versed). Such combinations should be avoided if possible.

PREGNANCY: Bicalutamide is not used for treating women.

NURSING MOTHERS: Bicalutamide is not used for treating women.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 4/6/2015

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