bicalutamide, Casodex (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Bicalutamide is used in combination with another medication, a luteinizing hormone-releasing hormone (LHRH) analog, to treat advanced prostate cancer.

SIDE EFFECTS: When bicalutamide and an LHRH analog are given together, the most common side effect is hot flashes (50% of patients) and facial flushing. Alcohol may worsen this reaction, and so it should be cautiously consumed.

Other common side effects of the combination are:

LHRH analogs may increase blood glucose and worsen diabetes. Less common side effects are breast enlargement and breast pain, which may be due to the bicalutamide alone.



PREPARATIONS: Tablet: 50 mg.

STORAGE: Bicalutamide should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

DOSING: Bicalutamide should be taken as one 50 mg tablet in the morning or evening at the same time each day. It may be taken with or without food. Once bicalutamide therapy has begun, it should not be interrupted or stopped without consulting a physician.

DRUG INTERACTIONS: Bicalutamide may interact with warfarin (Coumadin). Therefore, the dose of warfarin may need to be adjusted, and the ability of blood to clot should be closely monitored.

Medically Reviewed by a Doctor on 4/6/2015

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