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bexarotene - oral, Targretin

GENERIC NAME: BEXAROTENE - ORAL (bex-AR-oh-teen)

BRAND NAME(S): Targretin

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: This medication can cause severe birth defects if used during pregnancy. Women who are pregnant must not use bexarotene. If pregnancy occurs, notify your doctor immediately. You should have a pregnancy test and birth control counseling from your doctor before you start treatment with bexarotene and every month while you are taking the medication. Use 2 effective forms of birth control together (or completely avoid sexual intercourse) starting 1 month before treatment starts, during treatment, and for 1 month after you stop. One of your forms of birth control should be non-hormonal (e.g., barrier method such as condoms/cervical cap/diaphragm, copper coil IUD, or spermicide).

Males taking this medication should use a condom during sexual activity with a woman who is pregnant or may become pregnant, continuing until 1 month after their last dose.

USES: Bexarotene is used to treat skin problems from a certain type of cancer (cutaneous T-cell lymphoma-CTCL). It belongs to a class of drugs called retinoids (vitamin A derivatives). Bexarotene works by slowing or stopping the growth of cells.

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using bexarotene and each time you get a refill. If you have any questions, consult your doctor or pharmacist.Take this medication by mouth with or immediately after a meal, usually once daily or as directed by your doctor. The dosage is based on your body size, medical condition, and response to therapy. Swallow the medication whole. Do not crush or chew the medication. Do not use the capsule if it is broken or leaking. If the contents of the capsule touch your skin, immediately wash the area with soap and water and tell your doctor.Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.It may take up to several months of continued use to see a response to treatment. Your dosage may need to be adjusted by your doctor during this time.Since this drug can be absorbed through the skin, women who are pregnant or who may become pregnant should not handle this medication. Learn proper technique for safe handling and disposal of this medicine and its container. Consult your pharmacist.

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