betaxolol ophthalmic, Betoptic S, Betoptic (cont.)

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Medical and Pharmacy Editor:

DOSING: Both hands should be washed before each use of betaxolol or any other eye medication. The head should be tilted back and the lower lid pulled down with the index finger to form a pouch. The tip of the squeeze bottle should not be touch the eye or eyelid and become contaminated. The bottle should be squeezed slightly to allow the prescribed number of drops into the pouch. The eye is closed gently for 1 to 2 minutes without blinking. The usual dose is 1 drop in each affected eye twice daily. Safe use of beta blockers has been demonstrated in pediatric patients.

DRUG INTERACTIONS: Combined use of betaxolol ophthalmic solution with oral beta- adrenergic blocking agents, for example, propranolol (Inderal), atenolol (Tenormin), metoprolol (Lopressor) or carvedilol (Coreg) can result in additive effects. Thus, patients may experience excessively low blood pressure or reductions in heart rate.

PREGNANCY: It is unknown if the small amount of betaxolol that is absorbed into the blood after administration into the eye affects the fetus. Safe use of betaxolol during pregnancy has not been established.

NURSING MOTHERS: It is not known whether betaxolol is excreted into breast milk. Safe use of betaxolol during nursing thus has not been established.

SIDE EFFECTS: Ophthalmic betaxolol can cause side effects which are usually mild and transient. The most common side effect is transient ocular (temporary eye) discomfort. Blurred vision, itching, swelling, eye pain, and dryness may occur. Rarely, betaxolol eye drops can result in side effects that are seen with oral beta-adrenergic blockers. For example, persons can experience fatigue, insomnia, nausea, dizziness, lightheadedness, depression, slow heart rate, low blood pressure, cold extremities, and shortness of breath or wheezing.

Reference: FDA Prescribing Information

Last Editorial Review: 3/19/2013

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