betamethasone dipropionate, Diprolene; Diprolene AF; (Diprosone, Alphatrex have been discontinued)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Psoriasis Symptoms, Causes and Treatment

The suppression of inflammation and the immune response caused by steroid excess also allows infections to occur more easily.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Cream, ointment, lotion: 0.05%

STORAGE: All preparations should be kept at temperatures from 15 C to 30 C (59 F to 86 F). Lotion should be shaken before each use.

DOSING:

  • A thin strip of betamethasone cream or ointment is applied gently to the affected area once or twice daily.
  • A few drops of the lotion is applied to the affected area once or twice daily.
  • The lotion should be massaged gently until it disappears.

Large doses and prolonged use of betamethasone may cause large amounts to be absorbed into the body and suppress production of cortisol by the adrenal glands. Therefore, the lotion should not be used for longer than two weeks, and not more than 50 ml should be used per week. The augmented cream or ointment should be limited to 45 grams per week. Betamethasone should not be used with occlusive dressings because occlusive dressings increase absorption into the body.

DRUG INTERACTIONS: Combining topical steroids with topical anthralin may increase psoriasis symptoms. Therefore, topical steroids should be discontinued 1 week before starting anthralins.

PREGNANCY: Use of betamethasone in pregnant women has not been studied. When corticosteroids are given systemically (orally, intramuscularly or intravenously) to pregnant animals fetal abnormalities occur.

NURSING MOTHERS: It is not known if betamethasone is secreted in breast milk. Corticosteroids absorbed into the body may appear in breast milk and may cause harmful effects in breast fed infants.

Medically reviewed by Eni Williams, PharmD

REFERENCE: AHFS Drug Information. Prescribing Information for Diprolene

Medically Reviewed by a Doctor on 12/29/2014

Quick GuidePsoriasis Rashes, Symptoms, Treatments

Psoriasis Rashes, Symptoms, Treatments
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