Beta Blockers (cont.)

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For what conditions are beta blockers used?

Beta blockers are used for treating:

They also have been found to prevent further heart attacks and death after a heart attack. Other uses include the treatment of hyperthyroidism, akathisia (restlessness or inability to sit still), and anxiety. Some beta blockers reduce the production of aqueous humor in the eye and therefore are used for reducing pressure in the eye caused by glaucoma.

Are there any differences among beta blockers?

Beta blockers differ in the type of beta receptors they block and, therefore, their effects.

  • Non-selective beta blockers, for example, propranolol (Inderal), block β1 and β2 receptors and, therefore, affect the heart, blood vessels, and air passages.
  • Selective beta blockers, for example, metoprolol (Lopressor, Toprol XL) primarily block β1 receptors and, therefore, mostly affect the heart and do not affect air passages.
  • Some beta blockers, for example, pindolol (Visken) have intrinsic sympathomimetic activity (ISA), which means they mimic the effects of epinephrine and norepinephrine and can cause an increase in blood pressure and heart rate. Beta blockers with ISA have smaller effects on heart rate than agents that do not have ISA.
  • Labetalol (Normodyne, Trandate) and carvedilol (Coreg) block beta and alpha-1 receptors. Blocking alpha receptors adds to the blood vessel dilating effect of labetalol and carvedilol.
Medically Reviewed by a Doctor on 10/21/2013


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