Bernard-Soulier Disease Center - Irving, TXIrving Pediatrician Doctors for Bernard-Soulier DiseaseType of Physician: Pediatrician What is a Pediatrician? A certification by the Board of Pediatrics; practitioners are concerned with the physical, emotional, and social health of children from birth to young adulthood. Pediatric care encompasses a wide range of health services, from preventive health care to the diagnosis and treatment of acute and chronic diseases. The pediatrician understands the constantly changing status of his/her patients due to growth and development, and the consequent changing standards of "normal" for age. 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Bernard-Soulier Disease (Giant Platelet Syndrome)Read the Bernard-Soulier Disease (Giant Platelet Syndrome) article » What is Bernard-Soulier syndrome?The Bernard-Soulier Syndrome (B-SS) is a rare inherited bleeding disorder caused by abnormal platelets and subsequent abnormal clotting. It is one of the giant platelet syndromes. This syndrome was originally described in 1948 by two physicians who were treating a patient with a bleeding problem. They discovered that this patient had a prolonged bleeding time, fewer platelets, and larger platelets than the normal individual. Since then, the platelet abnormality has been described and determined to be due to the platelets lacking the ability to stick adequately to injured blood-vessel walls. This is a crucial aspect of the process of forming a blood clot, and as a result of this problem, there is abnormal bleeding. What are the symptoms and signs of Bernard-Soulier syndrome?Bernard-Soulier syndrome usually presents in the newborn period, infancy, or early childhood with bruises, nosebleeds (epistaxis), and/or gum (gingival) bleeding. Later problems can occur with anything that can induce bleeding such as menstruation, trauma, surgery, or stomach ulcers. What is the cause of Bernard-Soulier syndrome?Bernard-Soulier syndrome is a rare inherited disease and is transmitted in an autosomal recessive pattern. This means that both parents must carry a gene for the Bernard-Soulier syndrome and transmit that gene to the child for the child to have the disease. The prevalence is believed to be less than one in 1 million individuals. The molecular basis is now known and is due to a defect in the platelet glycoprotein complex 1b-IX-V. This is referred to as an adhesion complex and forms a receptor that enables platelets to stick together to form a clot. Normal platelets circulate in the blood and are the primary cells responsible for initiating clotting. Without this receptor, platelets cannot stick together and clotting does not occur no... Read the Bernard-Soulier Disease (Giant Platelet Syndrome) article » Recommended Reading Related to Bernard-Soulier Disease (Giant Platelet Syndrome)What is a bruise?You fall off your bike, bang your shin on the coffee table (that you swore you would move months ago) or run into a wall and wake up with a wallop of a bruise. What is a bruise, and what can you do about it? A bruise (medically referred to as a contusion) is caused when tiny blood vessels are damaged or broken as the result of a blow to the skin (be it bumping against something or hitting yourself with a hammer). The raised area of a bump or bruise results from blood leaking from these injured blood vessels into the tissues as well as from the body's response to the injury. A purplish, flat bruise that occurs when blood leaks out into the top layers of skin is referred to as an ecchymosis.
Why do bruises occur more frequently in some people than in others?The injury required to produce a bruise varies with age. While it may take quite a bit of force to cause a bruise in a young child, even minor ... Other Related Bernard-Soulier Disease ArticlesEmergency Contact for Irving
Nearby Irving Hospitals *![]() Baylor Medical Center at Irving ![]() Texas Specialty Hospital at Dallas ![]() Las Colinas Medical Center ![]() Children's Medical Center of Dallas ![]() LifeCare Specialty Hospital of Dallas ![]() UT Southwestern Medical Center University Hospital St Paul ![]() UT Southwestern Medical Center ![]() Irving Coppell Surgical Hospital ![]() Parkland Health & Hospital System ![]() UT Southwestern Medical Center University Hospital Zale Lipshy ![]() Texas Scottish Rite Hospital for Children ![]() Methodist Dallas Medical Center ![]() RHD Memorial Medical Center ![]() Renaissance Hospital Dallas ![]() Mary Shiels Hospital ![]() Harris Methodist HEB Hospital ![]() Harris Methodist Springwood ![]() Baylor Specialty Hospital ![]() Kindred Hospital Arlington ![]() Millwood Hospital ![]() Baylor Jack & Jane Hamilton Heart & Vascular Hospital ![]() Baylor University Medical Center ![]() Texas Health Memorial Hospital at Arlington ![]() Baylor Institute for Rehabilitation ![]() Baylor Regional Medical Center at Grapevine ![]() Arlington Rehabilitation Hospital ![]() Kindred Hospital Walnut Hill ![]() Presbyterian Hospital of Dallas ![]() Methodist Charlton Medical Center ![]() Dallas VA Medical Center ![]() HEALTHSOUTH Rehabilitation Hospital of Arlington ![]() Medical Center of Arlington ![]() Methodist Rehabilitation Hospital ![]() Medical City Children's Hospital ![]() Medical City Hospital ![]() Green Oaks Hospital ![]() Select Specialty Hospital South Dallas ![]() USMD Hospital at Arlington ![]() Kindred Hospital Dallas ![]() Southwest Surgical Hospital ![]() Hickory Trail Hopsital ![]() Timberlawn Mental Health System ![]() Doctors Hospital at White Rock Lake ![]() Kindred Hospital White Rock ![]() North Hills Hospital ![]() Trinity Medical Center ![]() Medical Center of Lewisville ![]() Baylor Regional Medical Center at Plano ![]() Regency Hospital of North Dallas ![]() Methodist Richardson Regional Medical Center ![]() Presbyterian Hospital of Plano ![]() Plano Specialty Hospital ![]() Kindred Hospital Mansfield ![]() Methodist Mansfield Medical Center ![]() Baylor Medical Center at Garland ![]() Baylor Specialty Hospital Garland ![]() Baylor Medical Center at Trophy Club ![]() HEALTHSOUTH Plano Rehabilitation Hospital ![]() Medical Center of Plano ![]() LifeCare Hospitals of Plano ![]() Dallas Regional Medical Center ![]() Baylor Medical Center at Frisco ![]() JPS Health Network ![]() HEALTHSOUTH Rehabilitation Hospital ![]() Harris Continued Care Hospital ![]() Harris Methodist Fort Worth ![]() Cook Children's Medical Center ![]() Kindred Hospital Fort Worth ![]() Baylor All Saints Medical Center at Fort Worth ![]() Plaza Medical Center of Fort Worth ![]() Baylor Surgical Hospital at Fort Worth ![]() Centennial Medical Center ![]() Denton Regional Medical Center ![]() Huguley Memorial Medical Center ![]() Lake Pointe Medical Center Featured Articles*Provider Directory Terms of Use: The WebMD 'Provider Directory' is provided by WebMD for use by the general public as a quick reference of information about Providers. The Provider Directory is not intended as a tool for verifying the credentials, qualifications, or abilities of any Provider contained therein. Inclusion in the Provider Directory does not imply recommendation or endorsement nor does omission in the Provider Directory imply WebMD disapproval. |






































































































