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- Is bepridil available as a generic drug?
- Do I need a prescription for bepridil?
- What are the uses for bepridil?
- What are the side effects of bepridil?
- What is the dosage for bepridil?
- Which drugs or supplements interact with bepridil?
- Is bepridil safe to take if I'm pregnant or breastfeeding?
- What else should I know about bepridil?
What is the dosage for bepridil?
Bepridil usually is taken once daily. It can be taken with meals or at bedtime if nausea is a problem.
Which drugs or supplements interact with bepridil?
- Bepridil can reduce the strength with which the heart muscle contracts. Drugs which also have this effect when given together with bepridil could seriously reduce contraction of the heart and possibly precipitate congestive heart failure. Such drugs include quinidine (Quinaglute; Duraquin; Quinidex), procainamide (Procan-SR; Pronestyl), disopyramide (Norpace), flecainide (Tambocor), verapamil (Calan; Isoptin; Covera; Verelan), diltiazem (Cardizem; Tiazac; Dilacor), and all beta-blockers, for example, atenolol (Tenormin).
- Bepridil slows the ability of the heart's muscle to recover electrically and get ready for the next contraction. Other drugs which have the same effect could interact with bepridil, possibly causing serious problems with abnormal heart rhythms and should be used cautiously if at all with bepridil. Such drugs include quinidine (Quinaglute; Duraquin; Quinidex), procainamide (Procan-SR; Pronestyl), disopyramide (Norpace), flecainide (Tambocor), and tricyclic antidepressants, for example, amitriptyline (Elavil, Endep).
- Bepridil may increase levels of digoxin (Lanoxin) in the blood, thereby increasing the risk of digoxin toxicity.
- Diuretics, for example, furosemide (Lasix), bumetanide (Bumex), torsemide Demadex), hydrochlorothiazide (Hydrodiuril), chlorthalidone (Hygroton), metolazone (Zaroxolyn) may cause a reduction in blood potassium concentrations thereby increasing the risk of bepridil-induced abnormal heart rhythms.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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