bepridil (Vascor, Bepadin - Discontinued)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for bepridil?

Bepridil usually is taken once daily. It can be taken with meals or at bedtime if nausea is a problem.

Which drugs or supplements interact with bepridil?

  • Bepridil can reduce the strength with which the heart muscle contracts. Drugs which also have this effect when given together with bepridil could seriously reduce contraction of the heart and possibly precipitate congestive heart failure. Such drugs include quinidine (Quinaglute; Duraquin; Quinidex), procainamide (Procan-SR; Pronestyl), disopyramide (Norpace), flecainide (Tambocor), verapamil (Calan; Isoptin; Covera; Verelan), diltiazem (Cardizem; Tiazac; Dilacor), and all beta-blockers, for example, atenolol (Tenormin).
  • Bepridil slows the ability of the heart's muscle to recover electrically and get ready for the next contraction. Other drugs which have the same effect could interact with bepridil, possibly causing serious problems with abnormal heart rhythms and should be used cautiously if at all with bepridil. Such drugs include quinidine (Quinaglute; Duraquin; Quinidex), procainamide (Procan-SR; Pronestyl), disopyramide (Norpace), flecainide (Tambocor), and tricyclic antidepressants, for example, amitriptyline (Elavil, Endep).
  • Bepridil may increase levels of digoxin (Lanoxin) in the blood, thereby increasing the risk of digoxin toxicity.
  • Diuretics, for example, furosemide (Lasix), bumetanide (Bumex), torsemide Demadex), hydrochlorothiazide (Hydrodiuril), chlorthalidone (Hygroton), metolazone (Zaroxolyn) may cause a reduction in blood potassium concentrations thereby increasing the risk of bepridil-induced abnormal heart rhythms.
Medically Reviewed by a Doctor on 9/21/2016
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: bepridil on RxList
RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Heart Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors