BEPRIDIL-ORAL, Vascor (cont.)

SIDE EFFECTS: This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness. Notify your doctor immediately if these effects continue or worsen. You may also experience diarrhea, heartburn, nausea, blurred vision, muscle cramps, headache, fatigue, drowsiness, ringing in the ears, flushing, trembling or shaking hands. These effects should disappear as your body adjusts to the medication. Inform your doctor if they continue or worsen. Notify your doctor if you develop any of these serious effects: trouble breathing, swelling of the hands or feet, unusual bleeding or bruising, chest pain. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular heartbeat. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: heart disease, heart arrhythmias, liver disease, kidney disease, blood disorders. Your doctor may do laboratory tests periodically while you are taking this medication to check your blood potassium level. This drug should be used only if clearly needed during pregnancy. Since small amounts of bepridil appear in breast milk; consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you may take including: beta-blockers (e.g., propranolol), intravenous (IV) calcium, digoxin, fentanyl, terfenadine, astemizole, drugs that can increase your heart-rate (e.g., asthma drugs, caffeine, pseudoephedrine). Report other drugs which affect the heart rhythm (QTc prolongation), such as: dofetilide, pimozide, quinidine, sotalol, procainamide, sparfloxacin, "water pills" (diuretics such as furosemide or hydrochlorothiazide). Ask your doctor or pharmacist for more details. Check the ingredients on all cough-and-cold products. Ask your doctor or pharmacist about the safe use of these products. Do not start or stop any medicine without doctor or pharmacist approval.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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