benztropine (Cogentin)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

View Parkinson's Disease Slideshow Pictures

Benztropine blocks the activity of acetylcholine and can cancel or interfere with the action of drugs that increase gastrointestinal motility (movement of food through the GI tract). Example of such drugs includes:

Umeclidinium (Incruse Ellipta) and tiotropium (Spiriva) may increase the anticholinergic side effects of benztropine. Coadminstration of these agents with benztropine is not recommended.

Benztropine may increase the blood levels of thiazide diuretics. Caution should be used when these agents are used together.

Benztropine may increase the risk of stomach ulcers from using potassium chloride (Klor-Con). Combination treatment with both agents is generally not recommended.

PREGNANCY: Benztropine has not been adequately evaluated in pregnant women. Due to the lack of conclusive safety data, benztropine should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. Benztropine is classified as FDA pregnancy risk category C.

NURSING MOTHERS: It is not known if benztropine is excreted in breast milk. However, antimuscarinic agents have been reported to suppress lactation in animals and decrease prolactin levels in the blood of nursing mothers. Due to the lack of safety data, benztropine should be used cautiously in females who are breastfeeding or avoided.

SIDE EFFECTS: Side effects associated with benztropine treatment include

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 11/21/2014

Quick GuideParkinson's Disease: Symptoms, Causes, Stages, and Treatment

Parkinson's Disease: Symptoms, Causes, Stages, and Treatment
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Newsletters

Get the latest health and medical information delivered direct to your inbox!

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors