PEDIATRIC DOSING: For drug induced extrapyramidal symptoms oral, intramuscular or intravenous doses are available.
- Children = 3 years of age have been treated (off-label) with 0.02 to 0.05 mg/kg/dose 1 to 2 times daily.
- Adolescents have been treated (off-label) with 1 to 4 mg every 12 to 24 hours.
DRUG INTERACTIONS: Co-adminstration of benztropine with other anticholinergic agents increases the risk of anticholinergic side effects such as:
Commonly used drugs with moderate to significant anticholinergic effects are:
- amantadine (Symmetral),
- amoxapine, bupropion (Wellbutrin),
- clozapine (Clozaril),
- cyclobenzaprine (Flexeril),
- disopyramide (Norpace),
- maprotiline (Ludiomil),
- olanzapine (Zyprexa),
- orphenadrine (Norflex),
- first generation antihistamines (for example, diphenhydramine),
- phenothiazine, and
- tricyclic anitdepressants.
Quick GuideParkinson's Disease: Symptoms, Causes, Stages, Treatment
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