benztropine (Cogentin)

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GENERIC NAME: benztropine

BRAND NAME: Cogentin

DRUG CLASS AND MECHANISM: Benztropine is an oral and injectable synthetic medication. It is structurally similar to atropine (AtroPen) and diphenhydramine (Benadryl). Benztropine has anticholinergic effects. Anticholinergic drugs block the action of acetylcholine, a neurotransmitter (chemical) that nerves use to communicate with other nerves.

In Parkinson's there is an imbalance between levels of dopamine and acetylcholine neurotransmitters. Benztropine helps restore balance by blocking the action of acetylcholine in the central nervous system (brain and spinal cord). Benztropine may also block the uptake and storage of dopamine in the central nervous system (CNS), resulting in the prolongation of the effects of dopamine. Benztropine was approved by the U.S. Food and Administration (FDA) in 1954.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Tablets: 0.5 mg, 1 mg, 2 mg
  • Solution for injection: 1 mg/ 1 ml

STORAGE: Tablets should be stored at room temperature between 15 C to 30 C (59 F to 86 F). Injection solution should be stored at controlled room temperature between 19.44 C and 25 C (68 F and 77 F).

PRESCRIBED FOR: Benztropine is used for the management of drug induced extrapyramidal disorders (except tardive dyskinesia). It is also used for the treatment of Parkinsonism or Parkinson's disease (movement disorder).

Medically Reviewed by a Doctor on 11/21/2014



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