STORAGE: Tablets should be stored at room temperature at or below 30 C (86 F) and protected from moisture.
- The usual starting dose of benazepril is 10 mg daily. If patients are taking a diuretic (water pill) the starting dose is 5 mg daily.
- Doses may be increased to 20-40 mg once daily or divided and administered twice daily.
DRUG CLASS AND MECHANISM:
- Benazepril is an ACE (angiotensin converting enzyme) inhibitor used for treating high blood pressure. Other ACE inhibitors include enalapril (Vasotec), quinapril (Accupril), captopril (Capoten), fosinopril (Monopril), ramipril (Altace), moexipril (Univasc) and trandolapril (Mavik). ACE is an enzyme in the body that causes the formation of angiotensin II. Angiotensin II causes contraction of the muscles surrounding arteries and constriction of arteries in the body, thereby elevating blood pressure. ACE inhibitors such as benazepril lower blood pressure by inhibiting the formation of angiotensin II, thus relaxing the arteries. Relaxing the arteries not only lowers blood pressure, but also improves the pumping efficiency of a failing heart and thereby benefits patients with heart failure.
- The FDA approved benazepril in June 1991.
REFERENCE: FDA Prescribing Information
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