OTHER SERIOUS SIDE EFFECTS:
Other serious side effects of benazepril include:
- Serious allergic reactions
- Increased potassium levels
- Kidney failure
- Low platelet count
PREPARATIONS: Tablets: 5, 10, 20, and 40 mg.
- Combining benazepril with potassium supplements, potassium containing salt substitutes, and potassium conserving diuretics such as amiloride (Moduretic), spironolactone (Aldactone), and triamterene (Dyazide, Maxzide), can lead to dangerously high blood levels of potassium.
- Combining benazepril or other ACE inhibitors with nonsteroidal anti-inflammatory drugs (NSAIDs) in patients who are elderly, fluid-depleted (including those on diuretic therapy), or with poor kidney function may result in reduced kidney function, including kidney failure. These effects usually are reversible.
- There have been reports that aspirin and other NSAIDs such as ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and many others), indomethacin (Indocin, Indocin-SR), and naproxen (Anaprox, Naprelan, Naprosyn, Aleve) may reduce the effects of ACE inhibitors. When taken with lithium (Eskalith, Lithobid), benazepril can increase lithium to toxic levels in the blood.
- Nitritoid reactions (symptoms include facial flushing, nausea, vomiting and hypotension) may occur when injectable gold (sodium aurothiomalate), used in the treatment of rheumatoid arthritis, is combined with ACE inhibitors, including benazepril.
PREGNANCY AND BREASTFEEDING SAFETY:
- ACE inhibitors, including benazepril, can be harmful to the fetus and should not be taken by pregnant women.
- A small amount of benazepril is excreted into breast milk. A newborn exclusively breastfed may ingest less than 0.1% of the maternal dose of benazepril.
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