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- What is benazepril, and how does it work (mechanism of action)?
- What brand names are available for benazepril?
- Is benazepril available as a generic drug?
- Do I need a prescription for benazepril?
- What are the uses for benazepril?
- What are the side effects of benazepril?
- What is the dosage for benazepril?
- Which drugs or supplements interact with benazepril?
- Is benazepril safe to take if I'm pregnant or breastfeeding?
- What else should I know about benazepril?
What is benazepril, and how does it work (mechanism of action)?
- Benazepril is an ACE (angiotensin converting enzyme) inhibitor used for treating high blood pressure. Other ACE inhibitors include enalapril (Vasotec), quinapril (Accupril), captopril (Capoten), fosinopril (Monopril), ramipril (Altace), moexipril (Univasc) and trandolapril (Mavik). ACE is an enzyme in the body that causes the formation of angiotensin II. Angiotensin II causes contraction of the muscles surrounding arteries and constriction of arteries in the body, thereby elevating blood pressure. ACE inhibitors such as benazepril lower blood pressure by inhibiting the formation of angiotensin II, thus relaxing the arteries. Relaxing the arteries not only lowers blood pressure, but also improves the pumping efficiency of a failing heart and thereby benefits patients with heart failure.
- The FDA approved benazepril in June 1991.
What brand names are available for benazepril?
Is benazepril available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for benazepril?
What are the uses for benazepril?
- Benazepril can be used alone or in combination with hydrochlorothiazide for treating high blood pressure.
- Like other ACE inhibitors it also is used for treating heart failure or diabetic nephropathy (kidney disease) although these are not FDA approved uses for benazepril.
What are the side effects of benazepril?
Benazepril is generally well tolerated and side effects are usually mild and transient. Side effects include:
- Abdominal pain
- Loss of taste
- Loss of appetite
- Nausea and vomiting
- Easy bruising or bleeding
- Chest pain
- Difficulty breathing
- Severe dizziness
- Numbness or tingling in the hands or feet
- A sore or swollen throat
A dry, persistent cough has been reported with the use of benazepril and other ACE inhibitors. Coughing resolves after discontinuing the medication.
In rare instances, liver dysfunction and skin yellowing (jaundice) have been reported with ACE inhibitors. Benazepril should not be taken by people with a known allergy to ACE inhibitors. Swelling of the facial tissues and even the upper airways has been reported with ACE inhibitors on very rare occasions, and can lead to serious breathing difficulties. In rare instances, low white blood cell counts have been reported with the use of one ACE inhibitor. Low white blood cells increase the patient's risk of infections.
Quick GuideHow to Lower Blood Pressure: Exercise Tips
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